Continuing from events begun in the Inhumans solo series and in Nova, Thraxon the Inhuman has taken over the populace and imprisoned the royal family, with the help of the Sphinx. Crystal and Lockjaw escape, and recuit the Fantastic Four to free the family. They deal with Thraxon with difficulty, defeating him only when the Sphinx cuts away his support. If they could barely handle the minion, what chance do they stand against the master?